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- 抗原 See all PITX3 抗体
- PITX3 (Pituitary Homeobox 3 (PITX3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PITX3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- PITX3 Antibody detects endogenous levels of total PITX3
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PITX3
- 亚型
- IgG
- Top Product
- Discover our top product PITX3 Primary Antibody
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anti-Pituitary Homeobox 3 (PITX3) (AA 10-200) antibody
PITX3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (AA 231-302) antibodyPITX3 适用: 小鼠, 大鼠, Cow WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) antibodyPITX3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠 IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (N-Term) antibodyPITX3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 绵羊, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (Internal Region) antibodyVerified PITX3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (AA 144-193) antibodyPITX3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 绵羊, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) (AA 1-70) antibodyPITX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Homeobox 3 (PITX3) antibodyPITX3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- WB 1:1000-3000 IHC 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- PITX3 (Pituitary Homeobox 3 (PITX3))
- 别名
- PITX3 (PITX3 产品)
- 别名
- CTPP4 antibody, CTRCT11 antibody, PTX3 antibody, pitx3 antibody, Ptx3 antibody, ak antibody, zgc:109716 antibody, pitx3-A antibody, xPitx3 antibody, paired like homeodomain 3 antibody, paired-like homeodomain 3 antibody, paired like homeodomain 3 L homeolog antibody, paired-like homeodomain transcription factor 3 antibody, paired-like homeodomain transcription factor Pitx3 antibody, PITX3 antibody, Pitx3 antibody, pitx3.L antibody, pitx3 antibody
- 背景
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Description: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state. Essential for the normal lens development and differentiation. Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins. Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle (By similarity).
Gene: PITX3
- 分子量
- 32 kDa
- 基因ID
- 5309
- UniProt
- O75364
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