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Klotho 抗体

KL 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262853
发货至: 中国
  • 抗原 See all Klotho (KL) 抗体
    Klotho (KL)
    适用
    • 30
    • 30
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 4
    • 2
    • 1
    克隆类型
    • 34
    • 13
    多克隆
    标记
    • 29
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Klotho antibody is un-conjugated
    应用范围
    • 33
    • 22
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Klotho Antibody detects endogenous levels of total Klotho
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Klotho
    亚型
    IgG
    Top Product
    Discover our top product KL Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    Klotho (KL)
    别名
    Klotho (KL 产品)
    别名
    alpha-kl antibody, KL antibody, LOC100223456 antibody, klotho antibody, Klotho antibody, KL antibody, Kl antibody, kl antibody, LOC100533542 antibody
    背景

    Description: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).

    Gene: KL

    分子量
    116kDa
    基因ID
    9365
    UniProt
    Q9UEF7
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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