IRF9 抗体 (Internal Region)
-
- 抗原 See all IRF9 抗体
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IRF9 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- IRF9 Antibody detects endogenous levels of total IRF9.
- 预测反应
- Horse,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IRF9, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IRF9 Primary Antibody
-
-
- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- 别名
- IRF9 (IRF9 产品)
- 别名
- IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
- 背景
-
Description: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene: IRF9
- 分子量
- 48 kDa
- 基因ID
- 10379
- UniProt
- Q00978
- 途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
-