HBXIP 抗体 (Internal Region)
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- 抗原 See all HBXIP 抗体
- HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HBXIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- HBXIP Antibody detects endogenous levels of total HBXIP.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HBXIP, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HBXIP Primary Antibody
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anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibody
HBXIP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G1 unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 1-91) antibodyHBXIP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) antibodyHBXIP 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 1-173) antibodyHBXIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 41-91) antibodyHBXIP 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibodyHBXIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibodyHBXIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
- 别名
- LAMTOR5 (HBXIP 产品)
- 别名
- HBXIP antibody, xip antibody, XIP antibody, 1110003H18Rik antibody, Hbxip antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, xip antibody, Lamtor5 antibody
- 物质类
- Viral Protein
- 背景
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Description: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Gene: LAMTOR5
- 分子量
- 22 kDa
- 基因ID
- 10542
- UniProt
- O43504
- 途径
- PI3K-Akt Signaling, Regulation of Cell Size
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