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HBXIP 抗体 (AA 1-91)

HBXIP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167073
发货至: 中国
  • 抗原 See all HBXIP 抗体
    HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
    抗原表位
    • 15
    • 3
    • 2
    • 1
    AA 1-91
    适用
    • 24
    • 3
    • 2
    宿主
    • 21
    • 3
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HBXIP antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Ragulator complex protein LAMTOR5 protein (1-91AA)
    亚型
    IgG
    Top Product
    Discover our top product HBXIP Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
    别名
    LAMTOR5 (HBXIP 产品)
    别名
    HBXIP antibody, xip antibody, XIP antibody, 1110003H18Rik antibody, Hbxip antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, xip antibody, Lamtor5 antibody
    物质类
    Viral Protein
    背景

    Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.

    Aliases: HBV X interacting protein antibody, HBV X-interacting protein antibody, HBX interacting protein antibody, HBX-interacting protein antibody, hbxip antibody, HBXIP_HUMAN antibody, Hepatitis B virus X interacting protein antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody, MGC71071 antibody, Ragulator complex protein LAMTOR5 antibody, XIP antibody

    UniProt
    O43504
    途径
    PI3K-Akt Signaling, Regulation of Cell Size
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