GNB2L1 抗体 (Internal Region)
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- 抗原 See all GNB2L1 抗体
- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNB2L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- GNB2L1 Antibody detects endogenous levels of total GNB2L1.
- 预测反应
- Pig,Zebrafish,Bovine,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GNB2L1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GNB2L1 Primary Antibody
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anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (Internal Region) antibody
Verified GNB2L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (C-Term) antibodyGNB2L1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 斑马鱼, 小鸡, 非洲爪蟾, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (C-Term) antibodyGNB2L1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 斑马鱼, Saccharomyces cerevisiae, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 93-317) antibodyGNB2L1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyGNB2L1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 30-290) antibodyGNB2L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 30-290) antibodyGNB2L1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 2-317) antibodyGNB2L1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyGNB2L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 221-317) antibodyGNB2L1 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
- 别名
- RACK1 (GNB2L1 产品)
- 别名
- MGC53289 antibody, GNB2L1 antibody, AL033335 antibody, GB-like antibody, Gnb2-rs1 antibody, Rack1 antibody, p205 antibody, RACK1 antibody, H12.3 antibody, HLC-7 antibody, PIG21 antibody, rack1 antibody, wu:fb80d08 antibody, wu:fk65d12 antibody, gnb2-rs1 antibody, h12.3 antibody, hlc-7 antibody, pig21 antibody, C12-3 antibody, c12.3 antibody, guanine nucleotide binding protein, beta 2, related sequence 1 antibody, receptor for activated C kinase 1 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 antibody, receptor for activated C kinase 1 L homeolog antibody, Guanine nucleotide-binding protein subunit beta-2-like 1 antibody, gnb2l1 antibody, RACK1 antibody, Rack1 antibody, rack1.L antibody, rack-1 antibody
- 背景
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Description: Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression (PubMed:23636399). Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (PubMed:28132843). Binds to and stabilizes activated protein kinase C (PKC), increasing PKC-mediated phosphorylation. May recruit activated PKC to the ribosome, leading to phosphorylation of EIF6. Inhibits the activity of SRC kinases including SRC, LCK and YES1. Inhibits cell growth by prolonging the G0/G1 phase of the cell cycle. Enhances phosphorylation of BMAL1 by PRKCA and inhibits transcriptional activity of the BMAL1-CLOCK heterodimer. Facilitates ligand-independent nuclear translocation of AR following PKC activation, represses AR transactivation activity and is required for phosphorylation of AR by SRC. Modulates IGF1R-dependent integrin signaling and promotes cell spreading and contact with the extracellular matrix. Involved in PKC-dependent translocation of ADAM12 to the cell membrane. Promotes the ubiquitination and proteasome-mediated degradation of proteins such as CLEC1B and HIF1A. Required for VANGL2 membrane localization, inhibits Wnt signaling, and regulates cellular polarization and oriented cell division during gastrulation. Required for PTK2/FAK1 phosphorylation and dephosphorylation. Regulates internalization of the muscarinic receptor CHRM2. Promotes apoptosis by increasing oligomerization of BAX and disrupting the interaction of BAX with the anti-apoptotic factor BCL2L. Inhibits TRPM6 channel activity. Regulates cell surface expression of some GPCRs such as TBXA2R. Plays a role in regulation of FLT1-mediated cell migration. Involved in the transport of ABCB4 from the Golgi to the apical bile canalicular membrane (PubMed:19674157). Promotes migration of breast carcinoma cells by binding to and activating RHOA (PubMed:20499158).
Gene: RACK1
- 分子量
- 35kDa
- 基因ID
- 10399
- UniProt
- P63244
- 途径
- cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity
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