GNB2L1 抗体 (AA 2-317)
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北京 101111
Quick Overview for GNB2L1 抗体 (AA 2-317) (ABIN3042427)
抗原
See all GNB2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-317
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原理
- Anti-RACK1 GNB2L1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RACK1 GNB2L1 Antibody (ABIN3042427). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RACK1 recombinant protein (Position: T2-R317). Human RACK1 shares 100% amino acid (aa) sequence identity with both mouse and rat RACK1.
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亚型
- IgG
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anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (Internal Region) antibody
Verified GNB2L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (C-Term) antibodyGNB2L1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 斑马鱼, 小鸡, 非洲爪蟾, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (C-Term) antibodyGNB2L1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 斑马鱼, Saccharomyces cerevisiae, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 93-317) antibodyGNB2L1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyGNB2L1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyGNB2L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 221-317) antibodyGNB2L1 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyGNB2L1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) (AA 71-120) antibodyGNB2L1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 斑马鱼, 小鸡, 非洲爪蟾, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1) antibodyKD Validated GNB2L1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2355 unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma." in: Molecular biology reports, Vol. 41, Issue 5, pp. 3393-9, (2015) (PubMed).
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: "Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma." in: Molecular biology reports, Vol. 41, Issue 5, pp. 3393-9, (2015) (PubMed).
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- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
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别名
- GNB2L1
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背景
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Synonyms: Guanine nucleotide-binding protein subunit beta-2-like 1;Cell proliferation-inducing gene 21 protein;Guanine nucleotide-binding protein subunit beta-like protein 12.3;Human lung cancer oncogene 7 protein;HLC-7;Receptor for activated C kinase;Receptor of activated protein kinase C 1;RACK1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;GNB2L1;HLC7, PIG21;
Tissue Specificity: In the liver, expressed at higher levels in activated hepatic stellate cells than in hepatocytes or Kupffer cells. Up-regulated in hepatocellular carcinomas and in the adjacent non-tumor liver tissue. .
Background: Guanine nucleotide-binding protein subunit beta-2-like 1, also known as RACK1 is a 32kDa protein that in humans is encoded by the GNB2L1 gene. It is mapped to 5q35.3. GNB2L1 is a major component of translating ribosomes, which harbor significant amounts of PKC. This gene can provide a physical and functional link between PKC signaling and ribosome activation. GNB2L1 is also a mediator of agonist-induced Ca (2+) release. What’s more, GNB2L1 is an essential component of an oxygen-independent mechanism for regulating HIF1A stability. Overexpression of GNB2L1 and PKC-alpha suppressed CLOCK-BMAL1 transcriptional activity, and GNB2L1 stimulated phosphorylation of BMAL1 by PKC-alpha in vitro.
Sequence Similarities: Belongs to the WD repeat G protein beta family.
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分子量
- 32 kDa
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基因ID
- 10399
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UniProt
- P63244
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途径
- cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity
抗原
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