-
- 抗原 See all EPH Receptor A8 (EPHA8) 抗体
- EPH Receptor A8 (EPHA8)
-
抗原表位
- Internal Region
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EPH Receptor A8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- EPHA8 Antibody detects endogenous levels of total EPHA8.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EPHA8, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EPHA8 Primary Antibody
-
anti-EPH Receptor A8 (EPHA8) (AA 70-150) antibody
EPHA8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 9A12D8 unconjugated
anti-EPH Receptor A8 (EPHA8) (AA 45-249) antibodyEPHA8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A8 (EPHA8) antibodyEPHA8 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- EPH Receptor A8 (EPHA8)
- 别名
- EPHA8 (EPHA8 产品)
- 别名
- TK antibody, tke17-a antibody, si:ch211-122l14.1 antibody, EPHA8 antibody, EEK antibody, EK3 antibody, HEK3 antibody, AW047546 antibody, Eek antibody, Hek3 antibody, mKIAA1459 antibody, EPH receptor A8 L homeolog antibody, EPH receptor A8 antibody, eph receptor A8 antibody, Eph receptor A8 antibody, epha8.L antibody, EPHA8 antibody, epha8 antibody, Epha8 antibody
- 背景
-
Description: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth (By similarity).
Gene: EPHA8
- 分子量
- 111kDa.
- 基因ID
- 2046
- UniProt
- P29322
- 途径
- RTK signaling
-
You are here:
