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DVL1 抗体

DVL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261389
发货至: 中国
  • 抗原 See all DVL1 抗体
    DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
    适用
    • 43
    • 24
    • 20
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    人, 小鼠, 大鼠
    宿主
    • 41
    • 2
    • 2
    克隆类型
    • 45
    多克隆
    标记
    • 20
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    • 2
    • 1
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    This DVL1 antibody is un-conjugated
    应用范围
    • 44
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    • 7
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    DVL1 Antibody detects endogenous levels of total DVL1
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DVL1
    亚型
    IgG
    Top Product
    Discover our top product DVL1 Primary Antibody
  • 应用备注
    WB 1:1000-3000 IHC 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
    别名
    DVL1 (DVL1 产品)
    别名
    DVL antibody, DVL1L1 antibody, DVL1P1 antibody, Dvl antibody, mKIAA4029 antibody, dvl-1 antibody, DSH antibody, DVL-1 antibody, dvl1 antibody, dvl2l antibody, Xdsh antibody, dsh1 antibody, dishevelled segment polarity protein 1 antibody, dishevelled, dsh homolog 1 (Drosophila) antibody, microRNA 6808 antibody, dishevelled segment polarity protein 1b antibody, dishevelled segment polarity protein 1 L homeolog antibody, DVL1 antibody, Dvl1 antibody, MIR6808 antibody, dvl1b antibody, dvl1.L antibody
    背景

    Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

    Gene: DVL1

    分子量
    75 kDa
    基因ID
    1855
    UniProt
    O14640
    途径
    WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
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