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CD11b 抗体 (Internal Region)

Name: CD11b 抗体 (Internal Region)
SKU: ABIN6260569
Availability: OutOfStock

ITGAM 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of CD11b using K562 whole cell lysates (CD11b 抗体 (Internal Region))

ABIN6274001 at 1/100 staining Human liver cancer tissue by IHC-P. (CD11b 抗体 (Internal Region))

IHC

ABIN6274001 staining HepG2 cells by ICC/IF. (CD11b 抗体 (Internal Region))

IF/ICC

3 images

(1 reference)

产品编号 ABIN6260569

发货至: 中国

Datasheet as PDF

抗原 See all CD11b (ITGAM) 抗体

CD11b (ITGAM) (Integrin alpha M (ITGAM))
抗原表位
16

14

10

7

6

6

5

5

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
251

160

62

33

17

17

16

14

11

7

7

5

5

2

2

1
人, 小鼠, 大鼠
宿主
132

102

95

4

1

1
兔
Compatible Secondaries
克隆类型
235

96

1
多克隆
标记
112

37

29

25

19

10

7

6

6

6

5

5

4

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD11b antibody is un-conjugated
应用范围
248

81

76

70

56

36

36

25

20

19

13

13

7

6

5

5

4

3

2

2

2

1

1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

特异性

ITGAM Antibody detects endogenous levels of total ITGAM.

预测反应

Bovine,Horse,Sheep,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ITGAM, corresponding to a region within the internal amino acids.

亚型

IgG

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应用备注

WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Yang, Yan, Feng: "Surfactant protein A is expressed in the central nervous system of rats with experimental autoimmune encephalomyelitis, and suppresses inflammation in human astrocytes and microglia." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 3555-3565, (2018) (PubMed).
抗原

CD11b (ITGAM) (Integrin alpha M (ITGAM))

别名

ITGAM (ITGAM 产品)

别名

CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody

背景

Description: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:28807980). In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity).
Gene: ITGAM

分子量

170 kDa

基因ID

3684

UniProt

P11215

途径

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation