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- 抗原 See all CASP14 抗体
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASP14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Caspase-14 Antibody detects endogenous levels of total Caspase-14.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Caspase-14, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CASP14 Primary Antibody
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anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 133-242) antibody
CASP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C9 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) antibodyCASP14 适用: 人, 小鼠, 大鼠, 犬, Gerbil WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 223-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (C-Term) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 17-248) antibodyCASP14 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 171-230) antibodyCASP14 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) antibodyCASP14 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-246) antibodyCASP14 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 155-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
- 别名
- CASP14 (CASP14 产品)
- 别名
- CASP14 antibody, MICE antibody, mini-ICE antibody, caspase 14, apoptosis-related cysteine peptidase antibody, caspase 14 antibody, caspase-14-like antibody, caspase-14 antibody, CASP14 antibody, Casp14 antibody, LOC485601 antibody, LOC780455 antibody
- 背景
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Description: Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum (PubMed:15556625). Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF (PubMed:16854378, PubMed:19960512). Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function (PubMed:25121097). Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD (PubMed:24743736).
Gene: CASP14
- 分子量
- 27kDa
- 基因ID
- 23581
- UniProt
- P31944
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