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CASP14 抗体 (AA 223-242)

CASP14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030293
发货至: 中国
  • 抗原 See all CASP14 抗体
    CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 223-242
    适用
    • 41
    • 18
    • 17
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 39
    • 6
    • 1
    克隆类型
    • 30
    • 16
    多克隆
    标记
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CASP14 antibody is un-conjugated
    应用范围
    • 28
    • 11
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 223-242 (KARKTNPEIQSTLRKRLYLQ-human) were used as the immunogen for this Caspase-14 antibody.
    亚型
    IgG
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    Discover our top product CASP14 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting points. Titration of the Caspase-14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Caspase-14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
    别名
    Caspase-14 (CASP14 产品)
    别名
    CASP14 antibody, MICE antibody, mini-ICE antibody, caspase 14, apoptosis-related cysteine peptidase antibody, caspase 14 antibody, caspase-14-like antibody, caspase-14 antibody, CASP14 antibody, Casp14 antibody, LOC485601 antibody, LOC780455 antibody
    背景
    Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene. CASP14 belongs the evolutionarily conserved caspase family. CASP14 was assigned to chromosome 19p13.1. Using Northern blot and semiquantitative RT-PCR analyses, it was showed that CASP14 was transcriptionally upregulated during maintenance of confluent cultures of human epidermal keratinocytes. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Caspase 14 seems to play a role in keratinocyte differentiation and cornification and probably regulates maturation of the epidermis by proteolytically processing filaggrin.
    UniProt
    P31944
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