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BAZ1B 抗体 (Internal Region)

BAZ1B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260206
发货至: 中国
  • 抗原 See all BAZ1B 抗体
    BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
    抗原表位
    • 15
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    Internal Region
    适用
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    宿主
    • 50
    • 4
    克隆类型
    • 42
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    多克隆
    标记
    • 23
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    This BAZ1B antibody is un-conjugated
    应用范围
    • 27
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    • 1
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    Western Blotting (WB), ELISA
    特异性
    BAZ1B Antibody detects endogenous levels of total BAZ1B.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human BAZ1B, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product BAZ1B Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
    别名
    BAZ1B (BAZ1B 产品)
    别名
    BAZ1B antibody, wstf antibody, wbscr9 antibody, wbscr10 antibody, LOC100220420 antibody, WBSCR10 antibody, WBSCR9 antibody, WSTF antibody, C87820 antibody, Wbscr9 antibody, fi60d02 antibody, im:7137554 antibody, wu:fi60d02 antibody, bromodomain adjacent to zinc finger domain 1B antibody, bromodomain adjacent to zinc finger domain, 1B antibody, bromodomain adjacent to zinc finger domain 1B S homeolog antibody, BAZ1B antibody, baz1b antibody, Baz1b antibody, baz1b.S antibody
    背景

    Description: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.

    Gene: BAZ1B

    分子量
    185 kDa
    基因ID
    9031
    UniProt
    Q9UIG0
    途径
    Nuclear Hormone Receptor Binding, Chromatin Binding
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