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ATP6AP1 抗体 (Internal Region)

ATP6AP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260131
发货至: 中国
  • 抗原 See all ATP6AP1 抗体
    ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 21
    • 13
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 17
    • 5
    克隆类型
    • 18
    • 4
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6AP1 antibody is un-conjugated
    应用范围
    • 15
    • 8
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    ATP6AP1 Antibody detects endogenous levels of total ATP6AP1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ATP6AP1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATP6AP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))
    别名
    ATP6AP1 (ATP6AP1 产品)
    别名
    16A antibody, ATP6IP1 antibody, ATP6S1 antibody, Ac45 antibody, CF2 antibody, VATPS1 antibody, XAP-3 antibody, XAP3 antibody, AC45 antibody, AI316502 antibody, AW108110 antibody, Atp6ip1 antibody, Atp6s1 antibody, C7-1 antibody, mFLJ00383 antibody, H+-ATPase antibody, ATPase H+ transporting accessory protein 1 antibody, ATPase, H+ transporting, lysosomal accessory protein 1 antibody, plasma membrane ATPase 4 antibody, ATP6AP1 antibody, Atp6ap1 antibody, LOC547525 antibody
    背景

    Description: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca2+-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

    Gene: ATP6AP1

    分子量
    52kDa
    基因ID
    537
    UniProt
    Q15904
    途径
    Proton Transport, SARS-CoV-2 Protein Interactome
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