ABCG8 抗体 (Internal Region)
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- 抗原 See all ABCG8 抗体
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCG8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- ABCG8 Antibody detects endogenous levels of total ABCG8.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ABCG8, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ABCG8 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
- 别名
- ABCG8 (ABCG8 产品)
- 别名
- DDBDRAFT_0167690 antibody, DDBDRAFT_0191232 antibody, DDB_0167690 antibody, DDB_0191232 antibody, zgc:172358 antibody, GBD4 antibody, STSL antibody, 1300003C16Rik antibody, AI114946 antibody, sterolin-2 antibody, ATP binding cassette subfamily G member 8 antibody, ATP-binding cassette sub-family G member 8 antibody, ABC transporter G family protein antibody, ATP-binding cassette, sub-family G (WHITE), member 8 antibody, ABCG8 antibody, PTRG_02054 antibody, abcG8 antibody, abcg8 antibody, Abcg8 antibody
- 背景
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Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Gene: ABCG8
- 分子量
- 76kDa
- 基因ID
- 64241
- UniProt
- Q9H221
- 途径
- Lipid Metabolism
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