IL36A/IL1F6 抗体 (Internal Region)
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- 抗原 See all IL36A/IL1F6 (IL1F6) 抗体
- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL36A/IL1F6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- IL1F6 Antibody detects endogenous levels of total IL1F6.
- 预测反应
- Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IL1F6, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IL1F6 Primary Antibody
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anti-Interleukin 1 Family, Member 6 (IL1F6) antibody
IL1F6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 35-61) antibodyIL1F6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25982 unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) antibodyIL1F6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 6-151) antibodyIL1F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
- 别名
- IL36A (IL1F6 产品)
- 别名
- Il1f6 antibody, Fil1 antibody, IL-1H1 antibody, IL1RP2 antibody, Il1f9 antibody, Il36a antibody, FIL1 antibody, FIL1(EPSILON) antibody, FIL1E antibody, IL-1F6 antibody, IL1(EPSILON) antibody, IL1F6 antibody, interleukin 36, alpha antibody, interleukin 1 family, member 6 (epsilon) antibody, interleukin 1 family, member 6 antibody, interleukin 36 alpha antibody, Il36a antibody, IL1F6 antibody, IL36A antibody, Il1f6 antibody
- 背景
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Description: Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, and the production of proinflammatory cytokines such as TNF-alpha, IL-8 and IL-6. In cultured monocytes upregulates expression of IL-1A, IL-1B and IL-6. In myeloid dendritic cells involved in cell maturation by upregulating surface expression of CD83, CD86 and HLA-DR. In monocyte-derived dendritic cells facilitates dendritic cell maturation and drives T-cell proliferation. May play a role in proinflammatory effects in the lung.
Gene: IL36A
- 分子量
- 25 kDa
- 基因ID
- 27179
- UniProt
- Q9UHA7
- 途径
- Cancer Immune Checkpoints
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