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- 抗原 See all ISL1 抗体
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ISL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- ISL1 Antibody detects endogenous levels of total ISL1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ISL1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ISL1 Primary Antibody
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anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibody
ISL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 1A1 unconjugated Recombinant Antibody
anti-ISL LIM Homeobox 1 (ISL1) (AA 1-346) antibodyISL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyMicroarray verified ISL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB381223 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- 别名
- ISL1 (ISL1 产品)
- 别名
- Xisl-1 antibody, Xislet-1 antibody, islet1 antibody, ISLET-1 antibody, ISLET1 antibody, Isl-1 antibody, islet-1 antibody, isl-1=homeobox antibody, Islet-1 antibody, ISL LIM homeobox 1 S homeolog antibody, ISL LIM homeobox 1 antibody, ISL1 transcription factor, LIM/homeodomain antibody, isl1.S antibody, ISL1 antibody, Isl1 antibody, isl1 antibody
- 背景
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Description: DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart (By similarity).
Gene: ISL1
- 分子量
- 39 kDa
- 基因ID
- 3670
- UniProt
- P61371
- 途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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