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Prostaglandin D2 Receptor 2 (PTGDR2) (Internal Region) 抗体

PTGDR2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258740
发货至: 中国
  • 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
    Prostaglandin D2 Receptor 2 (PTGDR2)
    抗原表位
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    Internal Region
    适用
    • 56
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    宿主
    • 50
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    克隆类型
    • 50
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    多克隆
    标记
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    非结合性
    应用范围
    • 27
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    GPR44 Antibody detects endogenous levels of total GPR44.
    预测反应
    Pig,Horse,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GPR44, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PTGDR2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    Prostaglandin D2 Receptor 2 (PTGDR2)
    别名
    PTGDR2 (PTGDR2 产品)
    别名
    CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
    背景

    Description: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

    Gene: PTGDR2

    分子量
    66 kDa
    基因ID
    11251
    UniProt
    Q9Y5Y4
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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