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Prostaglandin D2 Receptor 2 (PTGDR2) 抗体 (PE)

PTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 PE
产品编号 ABIN7505895
发货至: 中国
  • 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
    Prostaglandin D2 Receptor 2 (PTGDR2)
    适用
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    宿主
    • 53
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    大鼠
    克隆类型
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    单克隆
    标记
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    PE
    应用范围
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    Flow Cytometry (FACS)
    原理
    Anti-Hu CD294 PE
    特异性
    The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2), a G-protein-coupled seven-transmembrane protein expressed on Th2 cells, peripheral blood basophils and eosinophils.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human CD294 transfected rat cell line TART/B19-12.10
    克隆位点
    BM16
    亚型
    IgG2a
    Top Product
    Discover our top product PTGDR2 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    Prostaglandin D2 Receptor 2 (PTGDR2)
    别名
    CD294 (PTGDR2 产品)
    别名
    CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
    背景
    Prostaglandin D2 receptor 2,CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells, but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut, heart, and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.,DP2, PTGDR2, DL1R, CRTH2, GPR44
    基因ID
    11251
    UniProt
    Q9Y5Y4
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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