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- 抗原 See all SAMHD1 抗体
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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抗原表位
- pThr592
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SAMHD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Phospho-SAMHD1 (Thr592) Antibody detects endogenous levels of SAMHD1 only when phosphorylated at Thr592.
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human SAMHD1 around the phosphorylation site of Thr592.
- 亚型
- IgG
- Top Product
- Discover our top product SAMHD1 Primary Antibody
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anti-SAM Domain and HD Domain 1 (SAMHD1) antibody
SAMHD1 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) antibodySAMHD1 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 387-626) antibodySAMHD1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-314) antibodySAMHD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (Internal Region) antibodySAMHD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) antibodySAMHD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) antibodySAMHD1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 256-370) antibodySAMHD1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SAM Domain and HD Domain 1 (SAMHD1) (AA 426-657) antibodySAMHD1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- 别名
- SAMHD1 (SAMHD1 产品)
- 别名
- CHBL2 antibody, DCIP antibody, HDDC1 antibody, MOP-5 antibody, SBBI88 antibody, si:dkeyp-44b8.8 antibody, E330031J07Rik antibody, Mg11 antibody, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain, 1 antibody, SAMHD1 antibody, samhd1 antibody, Samhd1 antibody
- 背景
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Description: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827).
Gene: SAMHD1
- 分子量
- 72kDa
- 基因ID
- 25939
- UniProt
- Q9Y3Z3
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