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SAMHD1 产品

(SAM Domain and HD Domain 1 (SAMHD1))

Categories

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010].

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Featured SAMHD1 Categories

SAMHD1 抗体

High quality antibodies with extensive validation data.

SAMHD1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SAMHD1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SAMHD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IF, IHC, FACS, IHC (p)
Validations
  • (15)
Cat. No. ABIN1500798
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IF, FACS
Validations
  • (5)
Cat. No. ABIN1500800
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN525504
Quantity 50 μg
Datasheet Datasheet

Recommended SAMHD1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1156472
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1156473
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1156470
Quantity 96 tests
Datasheet Datasheet

Recommended SAMHD1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319138
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3076631
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3122719
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SAMHD1 Products

Martínez-Arribas, Requena, Pérez-Moreno, Ruíz-Pérez, Vidal, González-Pacanowska: "DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools." in: Cellular and molecular life sciences : CMLS, Vol. 77, Issue 8, pp. 1645-1660, (2020) (PubMed).

Deutschmann, Schneider, Gruska, Vetter, Thomas, Kießling, Wittmann, Herrmann, Schindler, Milbradt, Ferreirós, Winkler, Wiebusch, Gramberg: "A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1." in: Nature microbiology, Vol. 4, Issue 12, pp. 2273-2284, (2019) (PubMed).

Businger, Deutschmann, Gruska, Milbradt, Wiebusch, Gramberg, Schindler: "Human cytomegalovirus overcomes SAMHD1 restriction in macrophages via pUL97." in: Nature microbiology, Vol. 4, Issue 12, pp. 2260-2272, (2019) (PubMed).

Kim, Kim, Yoon, Scott, Shevach: "SAMHD1 Posttranscriptionally Controls the Expression of Foxp3 and Helios in Human T Regulatory Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 6, pp. 1671-1680, (2018) (PubMed).

Cenker, Stultz, McDonald: "Brain Microglial Cells Are Highly Susceptible to HIV-1 Infection and Spread." in: AIDS research and human retroviruses, Vol. 33, Issue 11, pp. 1155-1165, (2018) (PubMed).

Daddacha, Koyen, Bastien, Head, Dhere, Nabeta, Connolly, Werner, Madden, Daly, Minten, Whelan, Schlafstein, Zhang, Anand, Doronio, Withers, Shepard, Sundaram, Deng, Dynan, Wang, Bindra, Cejka et al.: "SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. ..." in: Cell reports, Vol. 20, Issue 8, pp. 1921-1935, (2018) (PubMed).

Oh, Ryoo, Park, Kim, Daly, Cho, Ahn: "A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature." in: Scientific reports, Vol. 8, Issue 1, pp. 84, (2018) (PubMed).

Jáuregui, Landau: "DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1." in: Scientific reports, Vol. 8, Issue 1, pp. 4153, (2018) (PubMed).

Hofmann, Vanwalscappel, Bloch, Landau: "TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes." in: Retrovirology, Vol. 13, Issue 1, pp. 83, (2017) (PubMed).

Stultz, Cenker, McDonald: "Imaging HIV-1 Genomic DNA from Entry through Productive Infection." in: Journal of virology, Vol. 91, Issue 9, (2017) (PubMed).

Synonyms and alternative names related to SAMHD1

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1), SAM domain and HD domain 1 (samhd1), SAM domain and HD domain, 1 (Samhd1), SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (Samhd1), CHBL2, DCIP, E330031J07Rik, HDDC1, Mg11, MOP-5, SBBI88, si:dkeyp-44b8.8

Protein level used designations for SAMHD1

  • SAM domain and HD domain-containing protein 1
  • dNTPase
  • dendritic cell-derived IFNG-induced protein
  • deoxynucleoside triphosphate triphosphohydrolase SAMHD1
  • monocyte protein 5
  • SAM domain- and HD domain-containing protein 1
  • IFN-gamma induced
  • interferon-gamma-inducible protein Mg11
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