MAP3K1 抗体 (pThr1402)
Quick Overview for MAP3K1 抗体 (pThr1402) (ABIN6256476)
抗原
See all MAP3K1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pThr1402
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                                            特异性
- Phospho-MEKK1 (Thr1402) Antibody detects endogenous levels of MEKK1 only when phosphorylated at Thr1400, which site historically referenced as Thr1402.
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                                            纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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                                            免疫原
- A synthesized peptide derived from human MEKK1 around the phosphorylation site of Thr1402.
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                                            亚型
- IgG
 
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                                            应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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                                            有效期
- 12 months
 
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    - MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
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                                            别名
- MAP3K1
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                                            背景
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                        Description: Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624). Gene: MAP3K1 
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                                            分子量
- 161 kDa
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                                            基因ID
- 4214
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                                            UniProt
- Q13233
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                                            途径
- MAPK Pathway, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
 抗原
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