Caspase 9 抗体 (pThr125)
Quick Overview for Caspase 9 抗体 (pThr125) (ABIN6256471)
抗原
See all Caspase 9 (CASP9) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pThr125
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                                            特异性
- Phospho-Caspase 9 (Thr125) Antibody detects endogenous levels of Caspase 9 only when phosphorylated at Threonine 125.
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                                            预测反应
- Pig,Bovine,Horse,Sheep
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                                            纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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                                            免疫原
- A synthesized peptide derived from human Caspase 9 around the phosphorylation site of Thr125.
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            有效期
- 12 months
 
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    - Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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                                            别名
- CASP9
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                                            背景
- 
                        Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Gene: CASP9 
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                                            分子量
- 47kDa
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                                            基因ID
- 842
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                                            UniProt
- P55211
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                                            途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
 抗原
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