BAD 抗体 (pSer155)
Quick Overview for BAD 抗体 (pSer155) (ABIN6256155)
抗原
See all BAD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer155
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特异性
- Phospho-BAD (Ser155) Antibody detects endogenous levels of BAD only when phosphorylated at Ser118, which site historically referenced as Ser155.
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预测反应
- Bovine,Horse,Sheep,Dog
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human BAD around the phosphorylation site of Ser155.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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别名
- BAD
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背景
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Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Gene: BAD
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分子量
- 23kDa
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基因ID
- 572
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UniProt
- Q92934
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途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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