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ATF6 抗体 (Internal Region)

Name: ATF6 抗体 (Internal Region)
SKU: ABIN6254886
Availability: OutOfStock

ATF6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of MDA MB 361 cell lysate, using ATF6 Antibody. (ATF6 抗体 (Internal Region))

ABIN6276289 at 1/100 staining Mouse lung tissue by IHC-P. (ATF6 抗体 (Internal Region))

IHC

2 images

(3 references)

产品编号 ABIN6254886

发货至: 中国

Datasheet as PDF

抗原 See all ATF6 抗体

ATF6 (Activating Transcription Factor 6 (ATF6))
抗原表位
16

15

13

8

6

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
85

43

33

4

4

4

3

3

1

1
人, 小鼠, 大鼠
宿主
73

12

1
兔
Compatible Secondaries
克隆类型
75

11
多克隆
标记
47

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1
This ATF6 antibody is un-conjugated
应用范围
77

27

27

24

17

16

15

11

7

6

6

3

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

ATF6 Antibody detects endogenous levels of total ATF6.

预测反应

Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ATF6, corresponding to a region within the internal amino acids.

亚型

IgG

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anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibody
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anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibody
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anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibody
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anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibody
ATF6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibody
ATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Lu, Chen, Tang, Wang, Zhang: "GRP78 silencing enhances hyperoxia-induced alveolar epithelial cell apoptosis via CHOP pathway." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1493-1501, (2018) (PubMed).

Chen, Li, Liu, Luo, Liao, Li, Liu, Cheng, Lu, Chen: "Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non-alcoholic steatohepatitis." in: Life sciences, Vol. 203, pp. 291-304, (2018) (PubMed).

Yang, He, Li, Zhang, He, Duan, Huang, Xiang: "SWNHs (Single-Wall Carbon Nanohorns) Supervises Endoplasmic Reticulum (ER) Stress in Hepatocellular Carcinoma." in: Journal of nanoscience and nanotechnology, Vol. 18, Issue 10, pp. 6740-6745, (2018) (PubMed).
抗原

ATF6 (Activating Transcription Factor 6 (ATF6))

别名

ATF6 (ATF6 产品)

别名

ATF-6-like antibody, GB16435 antibody, ATF6 antibody, Atf6 antibody, ATF6A antibody, 9130025P16Rik antibody, 9630036G24 antibody, AA789574 antibody, Atf6alpha antibody, ESTM49 antibody, activating transcription factor 6 antibody, uncharacterized LOC412432 antibody, activating transcription factor 6 S homeolog antibody, cyclic AMP-dependent transcription factor ATF-6 alpha antibody, ATF6 antibody, LOC412432 antibody, atf6.S antibody, LOC100122162 antibody, Atf6 antibody

背景

Description: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N9-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
Gene: ATF6

分子量

75kDa

基因ID

22926

UniProt

P18850

途径

ER-Nucleus Signaling, Unfolded Protein Response