p53 抗体
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北京 101111
Quick Overview for p53 抗体 (ABIN6253959)
抗原
See all p53 (TP53) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- BP53-12, produces mouse IgG2a immunoglobulins recognizes both wild and mutant forms of 53 kD protein, identified as p53 suppressor gene
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纯度
- PURE
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亚型
- IgG2a
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应用备注
- immunohistochemistry on paraffin tissue sections
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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别名
- p53
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背景
- Antigen distribution: p53 is a tumor suppressor gene encoding a nuclear phosphoprotein that plays an important role in the control of normal cell proliferation. p53 is expressed in peripheral blood and bone marrow cells of patents with some hematological malignance. p53 protein quantitation is of value to ascertain malignancy and provides additional parameter suitable for evaluation of residual disease and for the monitoring of therapy and might also be one of the methods to indicate early relapse [1]. Cellular Expression: Human carcinoma.
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途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
抗原
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