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Lambda-IgLC 抗体 (FITC)

GMP Grade Lambda-IgLC 适用: 人 FACS 宿主: 小鼠 Monoclonal HP6054 FITC
产品编号 ABIN6253021
发货至: 中国
  • 抗原 See all Lambda-IgLC products
    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Lambda-IgLC antibody is conjugated to FITC
    应用范围
    • 19
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    Flow Cytometry (FACS)
    产品特性
    The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
    纯化方法
    Purified
    纯度
    >95 %
    质量等级
    GMP Grade
    免疫原
    Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads
    克隆位点
    HP6054
    亚型
    IgG2a kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))
    别名
    Ig Lambda Light Chain (Lambda-IgLC 产品)
    背景
    The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
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