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Keratin 10 抗体

KRT10 适用: 人, 犬, Cat FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal SPM623 unconjugated
产品编号 ABIN6252296
发货至: 中国
  • 抗原 See all Keratin 10 (KRT10) 抗体
    Keratin 10 (KRT10)
    适用
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    人, 犬, Cat
    宿主
    • 71
    • 47
    • 1
    小鼠
    克隆类型
    • 62
    • 57
    单克隆
    标记
    • 65
    • 10
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    This Keratin 10 antibody is un-conjugated
    应用范围
    • 75
    • 55
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    • 36
    • 34
    • 22
    • 14
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.
    克隆位点
    SPM623
    亚型
    IgG1 kappa
    Top Product
    Discover our top product KRT10 Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT

    Optimal dilution of the Cytokeratin 10 antibody should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    Keratin 10 (KRT10)
    别名
    Cytokeratin 10 (KRT10 产品)
    别名
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    背景
    This mAb recognizes a protein of 56.5  kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
    基因ID
    3858
    UniProt
    P13645
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