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Keratin 6 抗体

KRT6 适用: 人, 小鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal KRT6-1702 unconjugated
产品编号 ABIN6252256
发货至: 中国
  • 抗原 See all Keratin 6 (KRT6) products
    Keratin 6 (KRT6)
    适用
    • 18
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 15
    • 3
    小鼠
    克隆类型
    • 17
    • 1
    单克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 6 antibody is un-conjugated
    应用范围
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant human CK6 protein was used as the immunogen for the Cytokeratin 6 antibody.
    克隆位点
    KRT6-1702
    亚型
    IgG2a kappa
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT

    Optimal dilution of the Cytokeratin 6 antibody should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    Keratin 6 (KRT6)
    别名
    Cytokeratin 6 (KRT6 产品)
    别名
    Krt2-6 antibody, Krt-2.6 antibody, keratin 6 antibody, Krt6 antibody
    背景
    This mAb recognizes a protein of 56  kDa, identified as Cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
    基因ID
    3853
    UniProt
    P02538
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