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Keratin 6 抗体 (C-Term)

KRT6 适用: 人, 马, Orang-Utan, Chimpanzee, Gibbon IF, FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal LHK6 unconjugated
产品编号 ABIN2742495
发货至: 中国
  • 抗原 See all Keratin 6 (KRT6) products
    Keratin 6 (KRT6)
    抗原表位
    C-Term
    适用
    人, 马, Orang-Utan, Chimpanzee, Gibbon
    宿主
    • 14
    • 3
    • 1
    小鼠
    克隆类型
    • 16
    • 2
    单克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 6 antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Human KRT6 / CK6 / Cytokeratin 6
    纯化方法
    Protein G purified
    免疫原
    A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-terminus of human Cytokeratin 6. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Horse (100%), Marmoset, Mouse, Rat, Ferret, Bat, Hamster, Elephant, Dog (91%), Sheep, Bovine (82%).

    Type of Immunogen: Synthetic peptide
    克隆位点
    LHK6
    亚型
    IgG2a kappa
  • 应用备注
    Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL)

    Usage: This antibody recognizes a protein of 56  kDa, identified as cytokeratin 6 (CK6) or Keratin 6. In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express Cytokeratin 6 and 16. Keratin 6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of Cytokeratin 6 is particularly associated with differentiation. ELISA: Order BSA-free antibody format for coating.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2°C to 8°C.
  • 抗原
    Keratin 6 (KRT6)
    别名
    KRT6 / CK6 / Cytokeratin 6 (KRT6 产品)
    别名
    Krt2-6 antibody, Krt-2.6 antibody, keratin 6 antibody, Krt6 antibody
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