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TFF1 抗体 (C-Term)

TFF1 适用: 人 IF, IHC (p) 宿主: 小鼠 Monoclonal BCEIP1 unconjugated
产品编号 ABIN6252128
发货至: 中国
  • 抗原 See all TFF1 抗体
    TFF1 (Trefoil Factor 1 (TFF1))
    抗原表位
    • 27
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 81
    • 18
    • 16
    • 13
    • 9
    宿主
    • 45
    • 43
    • 1
    小鼠
    克隆类型
    • 47
    • 42
    单克隆
    标记
    • 56
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TFF1 antibody is un-conjugated
    应用范围
    • 44
    • 35
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    • 29
    • 20
    • 13
    • 6
    • 6
    • 6
    • 4
    • 2
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    • 1
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    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    A C-terminus peptide was used as the immunogen for the TFF1 antibody.
    克隆位点
    BCEIP1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TFF1 Primary Antibody
  • 应用备注
    Immunofluorescence: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)

    Prediluted format: incubate for 30 min at RT (2)

    Titering of the TFF1 antibody may be required for optimal performance.

    1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    TFF1 (Trefoil Factor 1 (TFF1))
    别名
    TFF1 (TFF1 产品)
    别名
    BCEI antibody, D21S21 antibody, HP1.A antibody, HPS2 antibody, pNR-2 antibody, pS2 antibody, Bcei antibody, PS2 antibody, bcei antibody, d21s21 antibody, hp1.a antibody, hps2 antibody, p1 antibody, p1-a antibody, pnr-2 antibody, ps2 antibody, tff1 antibody, xP1 antibody, xp1-L antibody, xp1 antibody, TFF1 antibody, Ps2 antibody, trefoil factor 1 antibody, trefoil factor 1 S homeolog antibody, trefoil factor 1, gene 2 S homeolog antibody, TFF1 antibody, Tff1 antibody, tff1.S antibody, tff1.2.S antibody, LOC100358238 antibody
    背景
    TFF1/Breast cancer estrogen inducible protein pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. TFF1/pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. TFF1 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract.
    基因ID
    7031
    UniProt
    P04155
    途径
    EGFR Signaling Pathway
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