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ATG4D 抗体 (AA 326-356)

This anti-ATG4D antibody is a 兔 多克隆 antibody detecting ATG4D in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN6244157
发货至: 中国

Quick Overview for ATG4D 抗体 (AA 326-356) (ABIN6244157)

抗原

See all ATG4D 抗体
ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATG4D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB11866
  • 抗原表位

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    AA 326-356

    预测反应

    M, Pig

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326~356 amino acids surrounding S341 of human APG4D.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

    别名

    ATG4D

    背景

    APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

    分子量

    52922

    NCBI登录号

    NP_001268433, NP_116274

    UniProt

    Q86TL0

    途径

    Autophagy
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