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ATG4D 抗体 (C-Term)

ATG4D 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7567 unconjugated
产品编号 ABIN1944848
发货至: 中国
  • 抗原 See all ATG4D 抗体
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 441-470, C-Term
    适用
    • 60
    • 41
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 77
    • 13
    • 1
    克隆类型
    • 78
    • 13
    多克隆
    标记
    • 27
    • 8
    • 8
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ATG4D antibody is un-conjugated
    应用范围
    • 78
    • 37
    • 26
    • 26
    • 19
    • 15
    • 13
    • 6
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from the C-terminal region of human ATG4D.
    克隆位点
    RB7567
    亚型
    Ig Fraction
  • 应用备注
    IF: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).

    Melvin: "Make Milwaukee safe for babies: the Child Welfare Commission and the development of urban health centers, 1911-1912." in: Journal of the West, Vol. 17, Issue 2, pp. 83-93, (1980) (PubMed).

    Pontén, Westermark: "Properties of human malignant glioma cells in vitro." in: Medical biology, Vol. 56, Issue 4, pp. 184-93, (1978) (PubMed).

    Westermark, Pontén, Hugosson: "Determinants for the establishment of permanent tissue culture lines from human gliomas." in: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 81, Issue 6, pp. 791-805, (1974) (PubMed).

  • 抗原
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    别名
    ATG4D (ATG4D 产品)
    别名
    APG4-D antibody, APG4D antibody, AUTL4 antibody, 9830134P12Rik antibody, Apg4d antibody, Atg4dl antibody, Autl4 antibody, apg4d antibody, autophagy related 4D cysteine peptidase antibody, autophagy related 4D, cysteine peptidase antibody, autophagy related 4D, cysteine peptidase L homeolog antibody, ATG4D antibody, Atg4d antibody, atg4d.L antibody
    背景
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    分子量
    52922
    基因ID
    84971
    NCBI登录号
    NP_001268433, NP_116274
    UniProt
    Q86TL0
    途径
    Autophagy
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