ATG4D 抗体 (AA 381-474)
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- 抗原 See all ATG4D 抗体
- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
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抗原表位
- AA 381-474
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATG4D antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ATG4D
- 亚型
- IgG
- Top Product
- Discover our top product ATG4D Primary Antibody
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anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 441-470), (C-Term) antibody
ATG4D 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7567 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibodyATG4D 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43), (N-Term) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7563 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibodyATG4D 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7565 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibodyATG4D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11866 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 98-108) antibody (HRP)ATG4D 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 98-108) antibody (PE)ATG4D 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 98-108) antibody (PerCP)ATG4D 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
- 别名
- ATG4D (ATG4D 产品)
- 别名
- APG4-D antibody, APG4D antibody, AUTL4 antibody, 9830134P12Rik antibody, Apg4d antibody, Atg4dl antibody, Autl4 antibody, apg4d antibody, autophagy related 4D cysteine peptidase antibody, autophagy related 4D, cysteine peptidase antibody, autophagy related 4D, cysteine peptidase L homeolog antibody, ATG4D antibody, Atg4d antibody, atg4d.L antibody
- 背景
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Synonyms: APG4D, AUTL4, APG4-D, Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, ATG4D
Background: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
- 基因ID
- 84971
- UniProt
- Q86TL0
- 途径
- Autophagy
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