RAP1 抗体 (AA 1-399)
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- 抗原 See all RAP1 (TERF2IP) 抗体
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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抗原表位
- AA 1-399
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This TE2IP antibody is generated from a mouse immunized with a recombinant protein between 1-399 amino acids from human TE2IP.
- 克隆位点
- 1664CT768-14-43
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TERF2IP Primary Antibody
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anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) antibody
TERF2IP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (Center) antibodyTERF2IP 适用: 人, 小鼠 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 1-280) antibodyTERF2IP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 142-191) antibodyTERF2IP 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴, 兔, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 1-280) antibodyTERF2IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 1-280) antibodyTERF2IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) antibodyTERF2IP 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 215-264) antibodyTERF2IP 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 212-235) antibodyTERF2IP 适用: 人 WB 宿主: 小鼠 Monoclonal 78B356-1 unconjugated
anti-Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (AA 212-235) antibodyTERF2IP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. IHC-P: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
- 别名
- TERF2IP (TERF2IP 产品)
- 别名
- DRIP5 antibody, RAP1 antibody, Rap1 antibody, cRAP1 antibody, TERF2 interacting protein antibody, telomeric repeat binding factor 2, interacting protein antibody, TERF2IP antibody, Terf2ip antibody
- 背景
- Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'- TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes.
- 分子量
- 44260
- UniProt
- Q9NYB0
- 途径
- Cell Division Cycle, Telomere Maintenance
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