This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RAC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-192 amino acids from the C-terminal region of human RAC2.
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.