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SQSTM1 抗体 (Ser351)

The 兔 多克隆 anti-SQSTM1 antibody is suitable to detect SQSTM1 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN6242568
发货至: 中国
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Quick Overview for SQSTM1 抗体 (Ser351) (ABIN6242568)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SQSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB50742
  • 抗原表位

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    AA 346-379, Ser351

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    Sqstm1

    背景

    Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.

    分子量

    48163

    UniProt

    Q64337

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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