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Lamin A/C 抗体 (AA 465-498)

This 兔 多克隆 anti-Lamin A/C antibody (Clone RB48839) specifically detects Lamin A/C in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6242430
发货至: 中国
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Quick Overview for Lamin A/C 抗体 (AA 465-498) (ABIN6242430)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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宿主

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克隆类型

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多克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB48839
  • 抗原表位

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    AA 465-498

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LMNA(Lamin-A/C) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 465-498 amino acids from the Central region of human LMNA(Lamin-A/C).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Lamin A/C (LMNA)

    别名

    LMNA(Lamin-A/C)

    背景

    Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

    分子量

    74139

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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