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CD36 抗体 (CF®640R)

CD36 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 185-1G2 CF®640R
产品编号 ABIN6187755
发货至: 中国
  • 抗原 See all CD36 抗体
    CD36
    适用
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    宿主
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    小鼠
    克隆类型
    • 88
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    单克隆
    标记
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    This CD36 antibody is conjugated to CF®640R
    应用范围
    • 90
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse Monoclonal anti-CD36 (185-1G2), CF640R Conjugate
    产品特性
    This antibody recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV, Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4 % of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Stimulated human leukocytes
    克隆位点
    185-1G2
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD36 Primary Antibody
  • 应用备注
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    CD36
    别名
    CD36 (CD36 产品)
    别名
    BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody
    分子量
    80-90 kDa
    基因ID
    948, 120949
    UniProt
    P16671
    途径
    TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
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