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TRIM29 抗体 (AA 1-200)

TRIM29 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal TRIM29-1042 unconjugated
产品编号 ABIN6187597
发货至: 中国
  • 抗原 See all TRIM29 抗体
    TRIM29 (Tripartite Motif Containing 29 (TRIM29))
    抗原表位
    • 24
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200
    适用
    • 67
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 34
    • 32
    • 1
    小鼠
    克隆类型
    • 36
    • 31
    单克隆
    标记
    • 41
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM29 antibody is un-conjugated
    应用范围
    • 42
    • 24
    • 21
    • 19
    • 13
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-TRIM29 (TRIM29/1042), Purified, BSA-free
    产品特性
    This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein
    克隆位点
    TRIM29-1042
    亚型
    IgG2b kappa
    Top Product
    Discover our top product TRIM29 Primary Antibody
  • 应用备注
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    A431 cells. Tonsil or Squamous cell carcinoma.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    TRIM29 (Tripartite Motif Containing 29 (TRIM29))
    别名
    TRIM29 (TRIM29 产品)
    背景
    Ataxia telangiectasia group D complementing gene (ATDC), Tripartite motif-containing protein 29 (TRIM29),
    分子量
    66 kDa
    基因ID
    23650, 504115
    UniProt
    Q14134
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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