TRIM29 抗体 (AA 1-200)
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- 抗原 See all TRIM29 抗体
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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抗原表位
- AA 1-200
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRIM29 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-TRIM29 (TRIM29/1042), Purified, BSA-free
- 产品特性
- This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein
- 克隆位点
- TRIM29-1042
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TRIM29 Primary Antibody
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- 应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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A431 cells. Tonsil or Squamous cell carcinoma.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
- 别名
- TRIM29 (TRIM29 产品)
- 背景
- Ataxia telangiectasia group D complementing gene (ATDC), Tripartite motif-containing protein 29 (TRIM29),
- 分子量
- 66 kDa
- 基因ID
- 23650, 504115
- UniProt
- Q14134
- 途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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