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TRIM29 抗体 (AA 1-200) (Biotin)

This anti-TRIM29 antibody is a 小鼠 单克隆 antibody detecting TRIM29 in IF, FACS 和 IHC (f). Suitable for 人.
产品编号 ABIN6187551
发货至: 中国

Quick Overview for TRIM29 抗体 (AA 1-200) (Biotin) (ABIN6187551)

抗原

See all TRIM29 抗体
TRIM29 (Tripartite Motif Containing 29 (TRIM29))

适用

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宿主

  • 36
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小鼠

克隆类型

  • 37
  • 33
单克隆

标记

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This TRIM29 antibody is conjugated to Biotin

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

TRIM29-1041
  • 抗原表位

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    AA 1-200

    原理

    Mouse Monoclonal anti-TRIM29 (TRIM29/1041), Biotin Conjugate

    产品特性

    This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein

    亚型

    IgG2a kappa
  • 应用备注

    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    A431 cells. Tonsil or Squamous cell carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    TRIM29 (Tripartite Motif Containing 29 (TRIM29))

    别名

    TRIM29

    背景

    Ataxia telangiectasia group D complementing gene (ATDC), Tripartite motif-containing protein 29 (TRIM29),

    分子量

    66 kDa

    基因ID

    23650, 504115

    UniProt

    Q14134

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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