CD11c 抗体 (AA 637-827) (CF®594)
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- 抗原 See all CD11c (ITGAX) 抗体
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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抗原表位
- AA 637-827
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD11c antibody is conjugated to CF®594
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- Mouse Monoclonal anti-CD11c (ITGAX/1284), CF594 Conjugate
- 产品特性
- This antibody recognizes a protein of 145 kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human ITGAX protein fragment (aa 637-827) (exact sequence is proprietary)
- 克隆位点
- ITGAX-1284
- 亚型
- IgG2b
- Top Product
- Discover our top product ITGAX Primary Antibody
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anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody
ITGAX 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody (FITC)ITGAX 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal BU15 FITC
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145) antibodyITGAX 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 100-350) antibodyITGAX 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 猴 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU15 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 102-279) antibodyITGAX 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6G2D1 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145), (C-Term) antibodyITGAX 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21771 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 637-827) antibodyITGAX 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGAX-1242 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (N-Term) antibodyITGAX 适用: 人, 小鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Human dendritic cells. Human lymph nodes and tonsils.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- 别名
- CD11c (ITGAX 产品)
- 别名
- CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
- 背景
- CD11 antigen-like family member C|Complement component 3 receptor 4 subunit|Integrin alpha-X|integrin, alpha X (antigen CD11C (p150), alpha polypeptide)|Leu M5 alpha subunit|Leukocyte adhesion glycoprotein p150 95 alpha chain|Myeloid membrane antigen alpha subunit|p150/95
- 分子量
- 145 kDa
- 基因ID
- 3687, 248472
- UniProt
- P20702
- 途径
- Complement System, Activated T Cell Proliferation, Integrin Complex
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