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KRT17 抗体

KRT17 适用: 人, 大鼠, Cow, Pig, 山羊 WB, IF, FACS, IHC (fro) 宿主: 小鼠 Monoclonal E3 unconjugated
产品编号 ABIN6178097
发货至: 中国
  • 抗原 See all KRT17 抗体
    KRT17 (Keratin 17 (KRT17))
    适用
    • 121
    • 47
    • 29
    • 18
    • 13
    • 11
    • 5
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    • 1
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    • 1
    • 1
    人, 大鼠, Cow, Pig, 山羊
    宿主
    • 98
    • 34
    小鼠
    克隆类型
    • 87
    • 45
    单克隆
    标记
    • 54
    • 16
    • 9
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    • 4
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    • 4
    • 3
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    • 2
    • 2
    • 1
    • 1
    • 1
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    This KRT17 antibody is un-conjugated
    应用范围
    • 100
    • 44
    • 38
    • 29
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    • 26
    • 20
    • 18
    • 17
    • 13
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Mouse Monoclonal anti-Cytokeratin 17 (E3), Purified, BSA-free
    产品特性
    Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as ?epithelial stem cell? marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    The cytoskeletal fraction of rat colon epithelium
    克隆位点
    E3
    亚型
    IgG2b kappa
    Top Product
    Discover our top product KRT17 Primary Antibody
  • 应用备注
    Immunohistology frozen & formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    T24 cells or Skin. Bladder or Cervix.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    KRT17 (Keratin 17 (KRT17))
    别名
    Cytokeratin 17 (KRT17 产品)
    别名
    K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody
    背景
    K17, Keratin Type I Cytoskeletal 17, Keratin-17, KRT17, PCHC1
    分子量
    46 kDa
    基因ID
    3872, 2785
    UniProt
    Q04695
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