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KRT17 抗体

KRT17 适用: 人 WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2K5 unconjugated
产品编号 ABIN7250128
发货至: 中国
  • 抗原 See all KRT17 抗体
    KRT17 (Keratin 17 (KRT17))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This KRT17 antibody is un-conjugated
    应用范围
    • 102
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    产品特性
    Monoclonal Antibody
    纯化方法
    Protein A purification
    免疫原
    Synthetic Peptide
    克隆位点
    2K5
    亚型
    IgG
    Top Product
    Discover our top product KRT17 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    KRT17 (Keratin 17 (KRT17))
    别名
    CK-17 (KRT17 产品)
    别名
    K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody
    背景
    May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
    分子量

    Observed_MW: 48 kDa

    Calculated_MW: 48 kDa

    UniProt
    Q04695
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