CD79a 抗体 (AA 202-216) (CF®405S)
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- 抗原 See all CD79a (CD79A) 抗体
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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抗原表位
- AA 202-216
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD79a antibody is conjugated to CF®405S
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
- 原理
- Mouse Monoclonal anti-CD79a (IGA/1406), CF405S Conjugate
- 产品特性
- A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
- 克隆位点
- IGA-1406
- 亚型
- IgG3
- Top Product
- Discover our top product CD79A Primary Antibody
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- 应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- 别名
- CD79a (CD79A 产品)
- 别名
- CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
- 分子量
- 25-44 kDa
- 基因ID
- 973
- 途径
- BCR Signaling
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