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Desmin 抗体 (CF®640R)

DES 适用: 人, 小鼠, 大鼠, 小鸡, Hamster WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal DES-1711 CF®640R
产品编号 ABIN6171187
发货至: 中国
  • 抗原 See all Desmin (DES) 抗体
    Desmin (DES)
    适用
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    人, 小鼠, 大鼠, 小鸡, Hamster
    宿主
    • 108
    • 37
    • 2
    小鼠
    克隆类型
    • 103
    • 45
    单克隆
    标记
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    This Desmin antibody is conjugated to CF®640R
    应用范围
    • 113
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-Desmin (DES/1711), CF640R Conjugate
    产品特性
    Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain ?-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human full-length desmin protein
    克隆位点
    DES-1711
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DES Primary Antibody
  • 应用备注
    Immunohistology (formalin) 1-2 μg/mL
    • Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    SJRH30 Cells. Uterus or Leiomyosarcoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    Desmin (DES)
    别名
    Desmin (DES 产品)
    别名
    DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody
    背景
    CMD1I, CSM1, CSM2, DES, Intermediate filament protein
    分子量
    52 kDa
    基因ID
    1674, 594952
    UniProt
    P17661
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