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Recombinant TNFRSF8 抗体

TNFRSF8 适用: 人 FACS, IHC, IF 宿主: 兔 Monoclonal Ki-1-1747R unconjugated Recombinant Antibody
产品编号 ABIN6169015
发货至: 中国
  • 抗原 See all TNFRSF8 抗体
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    抗体类型
    Recombinant Antibody
    适用
    • 132
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    宿主
    • 87
    • 60
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    克隆类型
    • 89
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    单克隆
    标记
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    This TNFRSF8 antibody is un-conjugated
    应用范围
    • 100
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Recombinant Rabbit Monoclonal anti-CD30 / TNFRSF8 (Ki-1/1747R), Purified, BSA-free
    产品特性
    This antibody recognizes a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human full-length TNFRSF8 protein
    克隆位点
    Ki-1-1747R
    亚型
    IgG kappa
    Top Product
    Discover our top product TNFRSF8 Primary Antibody
  • 应用备注
    Immunohistology (formalin) 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA  pH 8.0 for 10-20 min followed by cooling at RT for 20 min
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Hodgkin s lymphoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    别名
    CD30 / TNFRSF8 (TNFRSF8 产品)
    别名
    CD30 antibody, D1S166E antibody, Ki-1 antibody, Cd30 antibody, Ki antibody, TNFRSF8 antibody, TNF receptor superfamily member 8 antibody, tumor necrosis factor receptor superfamily, member 8 antibody, TNFRSF8 antibody, Tnfrsf8 antibody
    背景
    CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
    分子量
    105-120 kDa
    基因ID
    943, 1314
    UniProt
    P28908
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