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TNC 抗体 (CF®568)

TNC 适用: 人 IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal T2H5 CF®568
产品编号 ABIN6167832
发货至: 中国
  • 抗原 See all TNC 抗体
    TNC (Tenascin C (TNC))
    适用
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    宿主
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    小鼠
    克隆类型
    • 63
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    单克隆
    标记
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    This TNC antibody is conjugated to CF®568
    应用范围
    • 71
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    • 15
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-Tenascin (T2H5), CF568 Conjugate
    产品特性
    In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Human breast carcinoma
    克隆位点
    T2H5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNC Primary Antibody
  • 应用备注
    Does not react with rat, others not known
    • Immunohistology formalin-fixed 2-4 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell, and lung carcinomas. Staining of normal fibroblasts serves as internal positive control

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    TNC (Tenascin C (TNC))
    别名
    Tenascin (TNC 产品)
    别名
    tn antibody, 150-225 antibody, GMEM antibody, GP antibody, HXB antibody, JI antibody, TN antibody, TN-C antibody, AI528729 antibody, C130033P17Rik antibody, Hxb antibody, Ten antibody, cytotactin antibody, tenascin-C antibody, P230 antibody, tenc antibody, wu:fk04d02 antibody, tenascin C L homeolog antibody, tenascin C antibody, tnc.L antibody, TNC antibody, MCYG_00667 antibody, tnc antibody, Tnc antibody
    背景
    Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC
    分子量
    210 kDa and 300 kDa
    基因ID
    3371, 143250
    UniProt
    P24821
    途径
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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