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TNC 抗体

TNC 适用: 人 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal T2H5 unconjugated
产品编号 ABIN94480
发货至: 中国
  • 抗原 See all TNC 抗体
    TNC (Tenascin C (TNC))
    适用
    • 78
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    • 37
    • 15
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    宿主
    • 70
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    • 1
    小鼠
    克隆类型
    • 64
    • 41
    单克隆
    标记
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    This TNC antibody is un-conjugated
    应用范围
    • 72
    • 26
    • 26
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    • 23
    • 16
    • 12
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody T2H5 recognizes tenascin C, a large hexameric extracellular matrix glycoprotein.
    交叉反应 (详细)
    Other not tested, Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Protein preparation from a homogenate of a human mammary tumour specimen.
    克隆位点
    T2H5
    亚型
    IgG1
    Top Product
    Discover our top product TNC Primary Antibody
  • 应用备注
    Immunohistochemistry (paraffin sections): Immunohistochemical detection of tenascin is valuable for studies of tissue differentiation and tumour growth. The antibody T2H5 is excellent for staining of paraffin-embedded tissue sections.
    Western blotting: Recommended dilution: 1-2 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Gulubova: "Immunohistochemical localization of collagen type III and type IV, laminin, tenascin and alpha-smooth muscle actin (alphaSMA) in the human liver in peliosis." in: Pathology, research and practice, Vol. 198, Issue 12, pp. 803-12, (2003) (PubMed).

    Faustino, van Garderen, Schalken, Nederbragt: "Tenascin expression in normal, hyperplastic, dysplastic and neoplastic canine mammary tissues." in: Journal of comparative pathology, Vol. 126, Issue 1, pp. 1-8, (2002) (PubMed).

    Ioachim, Charchanti, Briasoulis, Karavasilis, Tsanou, Arvanitis, Agnantis, Pavlidis et al.: "Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and ..." in: European journal of cancer (Oxford, England : 1990), Vol. 38, Issue 18, pp. 2362-70, (2002) (PubMed).

    Tökés, Hortoványi, Csordás, Kulka, Mózes, Hatalyák, Kádár: "Immunohistochemical localisation of tenascin in invasive ductal carcinoma of the breast." in: Anticancer research, Vol. 19, Issue 1A, pp. 175-9, (1999) (PubMed).

  • 抗原
    TNC (Tenascin C (TNC))
    别名
    Tenascin (TNC 产品)
    别名
    tn antibody, 150-225 antibody, GMEM antibody, GP antibody, HXB antibody, JI antibody, TN antibody, TN-C antibody, AI528729 antibody, C130033P17Rik antibody, Hxb antibody, Ten antibody, cytotactin antibody, tenascin-C antibody, P230 antibody, tenc antibody, wu:fk04d02 antibody, tenascin C L homeolog antibody, tenascin C antibody, tnc.L antibody, TNC antibody, MCYG_00667 antibody, tnc antibody, Tnc antibody
    背景
    Tenascin C,Tenascin C is an approximately 250 kDa extracellular matrix glycoprotein with important roles in the nervous system, as it promotes correct migration of growing axons during development and during neuronal regeneration. It is also involved in synaptic plasticity. Ligands of tenascin C are integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3, and alpha-V/beta-6. Similarly to neural cells, it also stimulates angiogenesis by promoting elongation and migration of endothelial cells.,TNC, Hexabrachion, Cytotactin, Neuronectin
    基因ID
    3371
    UniProt
    P24821
    途径
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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