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Podoplanin 抗体 (AA 24-126)

PDPN 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal PDPN-1433 unconjugated
产品编号 ABIN6167017
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    抗原表位
    • 12
    • 11
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-126
    适用
    • 77
    • 22
    • 4
    • 3
    • 1
    宿主
    • 54
    • 24
    • 6
    • 5
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 49
    • 45
    单克隆
    标记
    • 52
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    应用范围
    • 69
    • 33
    • 31
    • 24
    • 20
    • 16
    • 14
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse Monoclonal anti-Podoplanin (PDPN/1433), Purified, with BSA
    产品特性
    This antibody recognizes a muco-protein of 38-43 kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human Podoplanin (PDPN) protein fragment (aa24-126) (exact sequence is proprietary)
    克隆位点
    PDPN-1433
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDPN Primary Antibody
  • 应用备注
    Immunohistology (formalin) 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL Western blotting 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    HeLa Cells. Angiosarcoma or Mesothelioma.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    200 μg/mL
    缓冲液
    PBS/0.05 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    Podoplanin (PDPN)
    别名
    Podoplanin (PDPN 产品)
    别名
    PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
    分子量
    38-43 kDa
    基因ID
    10630, 468675
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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